PHYTIC ACID AND ALZHEIMER’S DISEASE
In the last newsletter I covered the benefits of the often reviled phytic acid. What started me on digging into the subject was actually this study done on Alzheimer’s disease.
Published in Medical Hypothesis (2009), this study found a link between pineal gland dysfunction and the development of Alzheimer’s disease.
Here is a summary of the study:
“The presence of lesions in the pineal gland, which may be attributable to different causes (old age, or exposure to cytotoxic materials or environmental contaminants), would result in development of calcification, the extent of which would increase with more severe injury, with lower concentrations of crystallization inhibitors (pyrophosphate and phytate) and/or with reduced ability of the immune system. Calcification of the pineal gland would lead to a loss of function, decreasing the excretion of melatonin. This reduction in melatonin would both generate a further increase in oxidative injury (because of a fall in antioxidant capacity) and would be responsible for an increase in the deposition of b-amyloid protein, which is associated with the development of Alzheimer’s disease. Therefore, a dearth of crystallization inhibitors could be a risk factor for development of Alzheimer’s disease, and this hypothesis should be further evaluated.” (Study)
If calcification of the pineal gland is one of the main causes of Alzheimer’s disease then an important strategy for prevention of Alzheimer’s is to inhibit this calcification from occuring.
Within the study it is stated: “… it is hypothesized that a lack of inhibitors of calcium salt crystallization, such as pyrophosphate and phytate, will favor calcification.”
According to Wikipedia, “Pyrophosphate occurs in synovial fluid, blood plasma, and urine at levels sufficient to block calcification…Currently, pyrophosphate analogues, e.g. alendronate, are in clinical use in osteoporosis and Paget’s disease…” Since “aldedronate” is fosamax, a bisphosphonate drug of highly dubious value, we do not want to consider that as an option for fighting pineal gland crystallization.
However, phytate (or phytic acid) is commonly available in plant foods (beans and grains), and so there exists yet another argument for including these foods in our diet (for more arguments see previous newsletter).
The study mentions melatonin as important, since “melatonin synthesis decreases with age in all humans, but this decline is more pronounced in Alzheimer’s patients. In fact, melatonin inhibits the formation of beta-amyloid protein.”
I am a firm believer in taking melatonin in supplemental form, mostly because city living causes a depletion of it. Melatonin is blocked by light at night (street lights), electromagnetic pollution (cell phone towers), and blue light (computer and smartphone screens). So, given that it is not only necessary for sleep, but also an anti-cancer and anti-aging compound, I believe we should supplement with it. This Alzheimer’s link is yet one more reason to do so.
One of the best de-calcifiers of soft tissue is vitamin K2, a deficiency of which has also been linked to the development of Alzheimer’s disease.
(Study)
Nutristart has a liquid vitamin K2 product available, a nutrient now considered essential to supplement with, given that it has been deficient in the modern diet since the advent of feeding grain feeding animals (1930’s).
Finally, I will point out that the worst element for contributing to calcification of the pineal gland is fluoride, and one should try to avoid ingesting it at all costs. And, the best way to remove fluoride from the body (along with bromides/flame retardants) is to take high amounts of iodine.
(Source) |