Probiotics and Infants
Gastrointestinal disturbances are commonly found in children with brain disorders such as autism, ADHD, and Asperger’s syndrome. To test the idea that supplementation with probiotics might protect children against the development of such conditions, Finish researchers followed up on a study that was originally designed to test the effect of probiotic supplementation in infancy, on the later development of eczema.
In the original study (double-blind, placebo-controlled) 150 mothers were given 10 billion units of Lactobacillus rhamnosus, or placebo, daily for 4 weeks before delivery. After delivery, the same amount of probiotic was given to the mothers who breastfed the infants, or directly to the infants if they were not being breastfed, for another 6 months.
In order to see if the probiotics would help prevent brain disorders, 75 of the infants who received the probiotic (not the placebo) were followed-up with for the next 13 years, being evaluated by child psychiatrists and neurologists.
Results showed that ADHD or AS was diagnosed in 17% of the children in the placebo and none in the group who received probiotics at the beginning of their lives. This study concluded that: “Probiotic supplementation early in life may reduce the risk of neuropsychiatric disorder development later in childhood possible by mechanisms not limited to gut microbiota composition.”
Pärtty A, Kalliomäki M, Wacklin P, Salminen S, Isolauri E. A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. Pediatr Res. 2015 Mar 11. (Study) |